Despite 5 million babies being born worldwide through IVF, for every cycle of IVF, less than a third of patients less than 35 years succeed. Many couples need to consider a second attempt. Having said that, a failed IVF can turn lives upside down and moving on can be a challenge!
At Gynaecworld we give the couple a lot of time and review the cycle carefully. From stimulation, to embryo transfer and luteal support, almost anything can be an issue, and most of these issues can be addressed in the successive attempts. Our team at Gynaecworld empathize with the couples who have had repeated failed fertility treatment cycles and look deeply into the causes of these failures.
The various reasons for a failed IVF are
- Implantation Failure: It is responsible for > 95% of failed IVFs. Genetic/chromosomal abnormalities in the embryo are the primary cause, the others being problems with the uterus like adenomyosis, fibroids, polyps, septum and poor blood supply. Hysteroscopic correction of endometrial cavity could improve pregnancy rates. Embryonic genetic make-up can be assessed by pre-implantation genetic screening. For thin endometrium and poor blood supply various medicines like aspirin, vaginal sildenafal could be used with promising results. To help release of embryos from a hard zona, which is the covering of egg, assisted hatching may be used. Thin endometrium also impairs implantation of the embryo.
Poor quality gametes: Poor quality eggs and sperms could be another possible reason for a failed IVF. Sometimes the ovaries overrespond and sometimes the response is poor. The quality of eggs after retrieval affects the fertilization and implantation potential. In some cases, donor eggs, sperms or embryos could be the only option.
Hydrosalpinx: Hydrosalpinx is the collection of fluid in the tube which usually follows some pelvic infection, surgical removal if hydroselpinges improves pregnancy rates from IVF
Endometriosis: The pregnancy rates can also be low in patients who have endometriosis. Endometriotic cysts are best removed before embarking on IVF.
Despite the tremendous advances in the field of Assisted Reproduction, there remain some unknown, unexplained causes of failed IVF. However, more often than not, by altering the stimulation protocols, using additional tests and drugs, third party reproduction, the dream of a successful IVF can be realized.
We, at Gynaecworld, are proud of our success rates in IVF, have treated many couples who approach us when they have lost hope. With all the latest technologies aboard, and with a brilliant team, who personally individualizes and customizes the whole process at every step, the IVF Center at Gynaecworld is the way forward for couples who need to feel involved in their treatment, rather than being part of a crowd.